|
|
|
Probe Type |
Normal Finding |
Fusion Pattern |
|
Acute Lymphocytic Leukemia |
t(12;21) |
Vysis TEL/AML1 DC SF t(12;21) |
2 red (21q22), 2 green (12p13) |
2 Red, 1 Green, 1 Yellow (one red is larger than the other and the
green signal can also be absent |
|
11q23(MLL) |
Vysis MLL del t(11q23) |
2 fused yellow |
1 red, 1 green, 1 fused yellow |
|
t(9;22) |
Vysis bcr/abl DC DF t(9;22) |
2 red (9q34), 2 green (22q11.2) |
1 red, 1 green, 2 fused yellow |
|
Vysis bcr/abl ES DC SF t(9;22) |
2 red (9q34), 2 green (22q11.2) |
1 large red, 1 small red, 1 green, 1 fused yellow |
|
t(8;14) |
Vysis IGH/MYC/CEP 8 TC DF t(8;14) |
2 red (8q24), 2 green (14q32), 2 aqua (8 centromere) |
1 red, 1 green, 2 fused yellow, 2 aqua |
|
|
|
Probe Type |
Normal Finding |
Fusion Pattern |
|
Acute Myelocytic Leukemia (AML) |
11q23(MLL) |
Vysis MLL del t(11q23) |
2 fused yellow |
1 red, 1 green, 1 fused yellow |
|
t(9;22) |
Vysis bcr/abl DC DF t(9;22) |
2 red (9q34), 2 green (22q11.2) |
1 red, 1 green, 2 fused yellow |
|
|
Vysis bcr/abl ES DC SF t(9;22) |
2 red (9q34), 2 green (22q11.2) |
1 large red, 1 small red, 1 green, 1 fused yellow |
|
t(8;21) |
Vysis AML1/ETO DC DF t(8;21) |
2 red (8q22), 2 green (21q22) |
1 red, 1 green, 2 fused yellow |
|
t(15;17) |
Vysis PML/RARA DC SF |
2 red (15q22), 2 green (17q21) |
1 red, 1 green, 1 fused yellow |
|
inv(16) |
Vysis INV 16 t(16q22) |
2 fused yellow |
1 red, 1 green, 1 fused yellow |
|
Trisomy 8 |
|
|
|
|
|
|
Probe Type |
Normal Finding |
Fusion Pattern |
|
Chronic Lymphocytic Leukemia (CLL) |
Trisomy 12 |
|
|
|
|
del 13(q14) |
Vysis D13S319 del t(13q14.3) |
2 red |
1 red |
|
del p53 |
Vysis del P53 t(17p13.1) |
2 red |
1 red |
|
ATM (11q22.3) |
|
|
|
|
|
|
Probe Type |
Normal Finding |
Fusion Pattern |
|
Chronic Myelocytic Leukemia (CML) |
t(9;22) |
Vysis bcr/abl DC DF t(9;22) |
2 red (9q34), 2 green (22q11.2) |
1 red, 1 green, 2 fused yellow |
|
|
Vysis bcr/abl ES DC SF t(9;22) |
2 red (9q34), 2 green (22q11.2) |
1 large red, 1 small red, 1 green, 1 fused yellow |
|
Trisomy 8 |
|
|
|
|
|
|
Probe Type |
Normal Finding |
Fusion Pattern |
|
Non-Hodgkins Lymphoma (NHL) |
t(11;14) |
Vysis IGH/CCND1 DC DF t(11;14) |
2 red (11q13), 2 green (14q32.3) |
1 red, 1 green, 2 fused yellow |
|
t(8;14) |
Vysis IGH/MYC/CEP 8 TC DF t(8;14) |
2 red (8q24), 2 green (14q32), 2 aqua (8 centromere) |
1 red, 1 green, 2 fused yellow, 2 aqua |
|
del p53 |
Vysis del P53 t(17p13.1) |
2 red |
1 red |
|
t(14;18) |
Vysis IGH/BCL2 DCDF t(14;18) |
2 red (18q22), 2 green (14q32.3) |
1 red, 1 green 2 fused yellow |
|
IgH |
|
|
|
|
|
|
Probe Type |
Normal Finding |
Fusion Pattern |
|
Multiple Myeloma |
del 13q14 |
Vysis D13S319 del t(13q14.3) |
2 red |
1 red |
|
del p53 |
Vysis del P53 t(17p13.1) |
2 red |
1 red |
|
t(11;14) |
Vysis IGH/CCND1 DC DF t(11;14) |
2 red (11q13), 2 green (14q32.3) |
1 red, 1 green, 2 fused yellow |
